The predictive value of serum PCT,CRP combined with IL-6 for intestinal obstruction after gastric cancer resection
Objective To investigate the predictive value of serum procalcitonin (PCT),C-reactive protein (CRP) and interleukin-6 (IL-6) in intestinal obstruction after gastrectomy.Methods A total of 80 patients who received gastrectomy in our hospital from June 2021 to June 2024 were selected in this study,6 patients with postoperative intestinal obstruction were selected as the study group,and 74 patients without postoperative intestinal obstruction were selected as the control group.The serum levels of CRP,PCT and IL-6 were compared between the two groups,the progno-sis and the predictive value of serum PCT and CRP combined with IL-6 in the study group was evaluated by receiver operating characteristic curve (ROC).Results The serum levels of CRP,PCT and IL-6 in study group were significantly higher than those in control group (P<0.05).The levels of CRP,PCT and IL-6 in patients with postoperative intestinal obstruction in poor prognosis group were higher than those in good prognosis group (P<0.05).ROC curve analysis showed that the area under curve (AUC) of serum CRP,PCT,IL-6 and combined detection were 0.728,0.654,0.750 and 0.869,and the sensitivity was 0.630,0.513,0.524 and 0.973,respectively.The specificities were 0.723,0.752,0.766 and 0.814,and the area un-der the ROC curve of combined detection was the largest and the sensitivity was the highest (P<0.05).Conclusion The detection of serum PCT and CRP combined with IL-6 can significantly improve the early prediction accuracy of intestinal obstruction after gastrectomy,and can more comprehen-sively reflect the postoperative inflammation,providing a strong basis for early clinical intervention,so as to improve the prognosis of patients.
万方数据
维普
