针灸和草药(英文)2024,Vol.4Issue(3) :405-419.DOI:10.1097/HM9.0000000000000130

党参对免疫系统的多层次调控

Multi-layered effects of Codonopsis Radix on the immune system

陈希瑜 邵瑞 王彧
针灸和草药(英文)2024,Vol.4Issue(3) :405-419.DOI:10.1097/HM9.0000000000000130

党参对免疫系统的多层次调控

Multi-layered effects of Codonopsis Radix on the immune system

陈希瑜 1邵瑞 2王彧1
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作者信息

  • 1. 天津中医药大学中西医结合学院
  • 2. 天津中医药大学组分中药国家重点实验室
  • 折叠

摘要

当前研究已揭示党参在调节免疫系统方面的巨大潜力,预示其作为治疗慢性炎症、心血管疾病、肿瘤及衰老等疾病的潜在候选药物前景广阔.然而,党参内含多种成分,各自展现出复杂的免疫活性,导致对其整体免疫调节特性的理解尚显不足.因此在一定程度上限制了党参在临床实践中的广泛推广与应用.鉴于此,本综述旨在系统评估党参对免疫系统的多维度影响,并深入剖析其潜在的调节机制.同时,通过对比党参中不同活性成分的免疫调节效果,本综述旨在为未来的免疫调节研究奠定坚实的理论基础,推动党参在医药领域的进一步开发与应用.

Abstract

Recent research has highlighted the potential of Codonopsis Radix to modulate the immune system,making it a promising candidate for treating chronic inflammatory and cardiovascular diseases,tumors,and aging.However,because of the complex immune activities of its various components,a comprehensive understanding of Codonopsis Radix immune-regulating properties is still lacking.This knowledge gap hinders its widespread utilization in clinical practice.Therefore,this review aimed to assess the impact of Codonopsis Radix on the immune system and elucidate its underlying mechanisms.Additionally,we compared the immunomodulatory effects of different active ingredients derived from Codonopsis Radix to provide a theoretical basis for future investigations on immunomodulation.

关键词

党参/免疫调节草药/免疫系统/中药/活性成分

Key words

Active ingredients/Codonopsis Radix/Immune system/Immunomodulation herbal medicine/Traditional Chinese medicine

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基金项目

Science and Technology Project of Haihe Laboratory of Modern Chinese Medicine(24HHZYSS00002)

National Key Research and Development Program of China(2022YFC3501800)

National Natural Science Foundation of China(82204878)

出版年

2024
针灸和草药(英文)
天津中医药大学,中华中医药学会

针灸和草药(英文)

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参考文献量142
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