首页|针刺联合认知功能训练治疗阿尔茨海默病的疗效观察

针刺联合认知功能训练治疗阿尔茨海默病的疗效观察

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目的 探讨针刺联合认知功能训练治疗阿尔茨海默病(AD)患者的疗效及对脂代谢的影响.方法 选取2019年4月至2021年4月AD患者100例,采用随机数字表法分为对照组和观察组各50例.两组患者均给予常规用药治疗,对照组在常规治疗基础上采用认知功能训练治疗,观察组在对照组基础上联合针刺治疗.比较两组血脂、简易智力状态检查量表(MMSE)评分、执行功能、抽象能力、定向力评分、左侧椎动脉(LVA)、右侧椎动脉(RVA)、右侧大脑中动脉(MCA)水平及疗效评价.结果 治疗后,与对照组比较,观察组TC、TG、LDL水平均较低(P<0.05);观察组语言能力、记忆力、注意力评分低于对照组(P<0.05);观察组执行功能、抽象能力、定向力评分高于对照组(P<0.05);与对照组比较,观察组LVA、RVA、MCA血流速度均较低(P<0.05);总治疗有效率较高(P<0.05).结论 针刺联合认知功能可显著改善AD患者血脂水平,及语言能力、记忆力、注意力、执行能力、定向力等,治疗效果显著.
Objective To explore the therapeutic effect of acupuncture combined with cognitive function training on patients with Alzheimer's disease(AD)and its influence on lipid metabolism.Methods A total of 100 patients admitted to the Psychosomatic Disorders Department of the Seventh People's Hospital of Shaoxing,Zhejiang Province from April 2019 to April 2021 were selected and divided into the control group and the combined treatment group with 50 patients each by random number table method.Both groups were treated with conventional medication,the control group was treated with cognitive function training on the basis of conventional treatment,and the combined treatment group was treated with acupuncture on the basis of the control treatment group.Serum lipid analysis,Simple Mental State Inventory(MMSE)score,executive function,abstract ability,orientation score,left vertebral artery(LVA),right vertebral artery(RVA),right middle cerebral artery(MCA)level and clinical efficacy evaluation of the two groups were compared.Results After treatment,the levels of cholesterol total(TC),glycerin trilaurate(TG)and low-density lipoprotein(LDL)in the combined treatment group were lower than those in the control group(P<0.05).The language ability,memory and attention scores of the combined treatment group were lower than those of the control group(P<0.05).The scores of executive function,abstract ability and orientation in the combined treatment group were higher than those in the control group(P<0.05).Compared with the control group,the levels of LVA,RVA and MCA in the combined treatment group were lower.The total effective rate was higher(P<0.05).Conclusion Acupuncture combined with cognitive function can significantly improve the serum lipid level,language ability,memory,attention,executive ability and orientation of patients with AD,and the therapeutic effect is remarkable.

AcupunctureCognitive functionAlzheimer diseaseLipid metabolism

彭玲、谢渭根、凌迎春

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312000 浙江省绍兴市第七人民医院

针刺 认知功能 阿尔茨海默病 脂代谢

浙江省医药卫生科技计划项目

2022KY1309

2024

浙江临床医学
浙江中医药大学 浙江省科普作家协会医学卫生委员会

浙江临床医学

影响因子:0.52
ISSN:1008-7664
年,卷(期):2024.26(1)
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