Objective To analyze the infection status and epidemiological characteristics of common pathogens of acute respiratory infections(ARI)in hospitalized children at different age stages,and to provide a basis for the prevention and treatment of ARI in children in this region.Methods 1650 nasopharyngeal swab specimens from children with ARI who were treated at Quzhou People's Hospital from April 2023 to August 2023 were collected,and six common respiratory pathogens were detected using real-time fluorescence multiple reverse transcription polymerase chain reaction(RT PCR).Collected general information on children,grouped them according to gender and age(0～<12 months,1～<4 years,4～<7 years,7～14 years),and analyzed the distribution and epidemic characteristics of pathogens.Results Among the 1650 pediatric samples,874 cases detected one or more respiratory pathogens,with a detection rate of 53.0%.The incidence rate of each pathogen was 28.1%in mycoplasma pneumonia(MP),20.3%in respiratory syncytial virus(RSV),4.7%in human rhinovirus(HRV),2.1%in adenovirus(ADV),0.4%in influenza virus A(FluA),and 0.1%in influenza virus B(FluB)from high to low.There were 60 cases of multiple infections in children(detected by two or more pathogens).The most common cases of multiple infections were RSV+HRV(30.0%),and 2 cases were triple infections(3.3%).There was a statistically significant difference in pathogen detection among different age groups(χ2=56.450,P<0.01).The highest incidence of pathogens in the 7-14 year old age group was 63.7%,and there was a significant difference in the incidence of pathogens among different age groups.Among single pathogen infections,the detection rate of RSV was highest in children aged 1 to<4 years(27.7%,163/588),while the detection rate of MP was highest in children aged 7 to 14 years(57.7%,221/383).There were statistically significant differences in MP and RSV among the four groups of children(P<0.05).Various common pathogens are detected every month.Conclusion MP and RSV are the main pathogens causing ARI in hospitalized children in Quzhou area,and the detection rate of different pathogens is closely related to the age of hospitalized children.The presence of pathogens is mainly in the form of simple infection.And in multiple infections,double infection is the main form.Strengthening the monitoring of respiratory pathogens and expanding the scope of monitoring are crucial for the prevention and treatment of ARI in children.
万方数据
维普
