Objective To discusses the third lumbar skeletal muscle index(L3-SMI)and its correlation with clinical indicators and nutritional status in Crohn's disease(CD)patients.Methods This retrospective analysis included the clinical data of 156 CD patients who were admitted to the Department of Gastroenterology in our hospital from June 2018 to October 2022.We recorded the general clinical data,laboratory test results,and the score of nutritional risk screening 2002(NRS2002).We calculated the L3-SMI and compared these variables with patients with different L3-SMI levels.Results The low L3-SMI group had significantly higher age,height,number of NRS2002≥3,platelet count,erythrocyte sedimentation rate,high-sensitivity C-reactive protein,and faecal calprotectin than the high L3-SMI group.Conversely,the low L3-SMI group had significantly lower BMI,25-Hydroxyvitamin D,total protein,albumin,haemoglobin,and lymphocyte count than the high L3-SMI group.Spearman's correlation analysis indicated that L3-SMI was positively correlated with BMI,25-hydroxyvitamin D,albumin,haemoglobin,and an absolute number of lymphocytes.In contrast,it was negatively correlated with NRS2002≥3,platelet count,erythrocyte sedimentation rate,high-sensitivity C-reactive protein,and faecal calprotectin.Conclusion L3-SMI has a certain value in evaluating the nutritional status of CD patients and can be used as a comprehensive evaluation method for malnutrition in CD patients.
Crohn's diseaseNutritional riskMalnutritionSkeletal muscle index
维普
万方数据
