首页|营养治疗对晚期重症肺癌患者生活质量和预后的影响

营养治疗对晚期重症肺癌患者生活质量和预后的影响

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目的 探讨营养治疗对晚期重症肺癌患者生活质量及预后的影响.方法 收集2020年1月至2023年2月晚期重症肺癌患者103例,根据有无营养治疗分为观察组(有营养治疗,n=74)与对照组(无营养治疗,n=29).比较两组患者日常生活能力量表(ADL)评分降级的持续时间及治疗前后预后营养指数(PNI)、血清总蛋白、白蛋白、淋巴细胞绝对值、血红蛋白差值,并分析营养治疗的安全性.结果 观察组ADL评分降级持续时间低于对照组,差异有统计学意义(P<0.05).观察组治疗前后PNI、血清总蛋白、白蛋白、淋巴细胞绝对值、血红蛋白降低程度低于对照组,差异均有统计学意义(P<0.05).营养治疗不良反应占9.5%,所有患者均可耐受.结论 营养治疗有助于改善晚期重症肺癌患者的生活质量、预后及营养状况,并具有较好的安全性.
Objective To investigate the effect of nutritional therapy on quality of life,prognosis and nutritional status of patients with advanced severe lung cancer.Methods 103 patients with advanced severe lung cancer attending our hospital from January 2020 to February 2023 were collected and divided into the observation group(with nutritional therapy,n=74)and the control group(without nutritional therapy,n=29)according to the presence or absence of nutritional therapy.The duration of activity of daily living scale(ADL)degradation and differences of prognostic nutritional index(PNI),serum total protein,albumin,lymphocyte absolute value,and hemoglobin before and after treatment were measured and the safety of nutritional therapy were analyzed.Results The duration of ADL degradation in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The degree of reduction of PNI,total serum protein,albumin,absolute value of lymphocytes and hemoglobin in the observation group before and after treatment was lower than that in the control group,and the differences were statistically significant(P<0.05).Adverse reactions of nutritional therapy accounted for 9.5%,which could be tolerated by all patients.Conclusion Nutritional therapy can improve the quality of life,prognosis and nutritional status of patients with advanced severe lung cancer,and has good security.

Advanced severe lung cancerNutritionQuality of lifePrognosisTolerance

王洒、胡豪坤、李永强、丁飞

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311121 杭州师范大学

310015 杭州师范大学附属医院

晚期重症肺癌 营养 生活质量 预后 耐受性

2024

浙江临床医学
浙江中医药大学 浙江省科普作家协会医学卫生委员会

浙江临床医学

影响因子:0.52
ISSN:1008-7664
年,卷(期):2024.26(1)
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