Objective To explore the role of early comprehensive intervention in preventing venous thromboembolism(VTE)in patients with Alzheimer disease.Methods Selected 100 Alzheimer disease patients who met the diagnostic criteria of the International Classification of Diseases,10th edition,and had a hospitalization period of more than 3 months from July 2021 to December 2022.They were randomly divided into the observation group and the control group,with 50 patients in each group,using a random number table method.The observation group received early comprehensive intervention on the basis of routine nursing intervention,while the control group received routine nursing intervention.After 3 months of intervention,the incidence of VTE,D-dimer,fibrinogen levels,venous blood flow velocity in both lower limbs,and swelling in both lower limbs were compared between the two groups of patients during hospitalization.Results Early comprehensive intervention can reduce D-dimer levels and fibrinogen levels,and improve venous blood flow velocity(P<0.05).Conclusion Early comprehensive intervention for patients with moderate to severe Alzheimer disease can prevent the occurrence of venous thrombosis,which is of great significance for improving the quality of life of patients.
Early comprehensive interventionAlzheimer diseaseVenous thromboembolism