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高选择性翼管神经切断术对过敏性鼻炎患者的疗效

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目的 探讨高选择性性翼管神经切断术治疗过敏性鼻炎(AR)的效果及相关影响因素.方法 收集2018年1月至2023年3月39例因中重度持续性AR行鼻内镜下高选择性翼管神经切断术患者的临床资料,根据术前及术后6个月、12个月生活质量、主观症状进行疗效评估并分组,即有效组及无效组,分析影响远期手术疗效的因素.结果 39例患者术后6个月、12个月鼻结膜炎生活质量问卷(RQLQ)评分、主观症状视觉模拟评分(VAS)比术前更低(P<0.05).无效组合并鼻息肉及哮喘患者比有效组高(P<0.05).Logistic回归分析结果显示,合并鼻息肉及哮喘均为影响AR患者远期手术疗效的危险因素.结论 对AR患者行高选择性翼管神经切断术可获得较满意的疗效,合并鼻息肉及哮喘是影响远期手术疗效的危险因素.
Objective To investigate the effect and related influencing factors of highly selective pterygotomy in the treatment of allergic rhinitis(AR).Methods Clinical data of 39 patients who underwent nasal endoscopic highly selective pterygotomy due to moderate to severe persistent AR from January 2018 to March 2023 were collected.Efficacy was evaluated according to quality of life and subjective symptoms before and 6 months and 12 months after surgery,and the patients were divided into the effective group and the ineffective group,and then the factors affecting the long-term surgical efficacy were analyzed.Results The scores of nasal conjunctivitis Quality of Life questionnaire(RQLQ)and visual analogue scale of subjective symptoms(VAS)at 6 and 12 months after operation were lower than those before operation(P<0.05).The number of patients with invalid combination and nasal polyp and asthma was higher in the effective group(P<0.05).Logistic regression equation analysis showed that nasal polyp and asthma were both risk factors affecting the long-term surgical outcome of AR patients.Conclusion Pterygotomy can be a satisfactory treatment for AR patients,but from the perspective of long-term efficacy,nasal polyps and asthma are the risk factors affecting the surgical efficacy.

Allergic rhinitisHighly selective pterygotomyClinical effectInfluencing factor

杜慧慧、朱凯铨、麻琼钒、郑国君

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325000 浙江省温州市中西医结合医院

325000 温州医科大学附属第一医院

过敏性鼻炎 高选择性翼管神经切断术 临床疗效 影响因素

温州市基础性公益科研项目

Y20220857

2024

浙江临床医学
浙江中医药大学 浙江省科普作家协会医学卫生委员会

浙江临床医学

影响因子:0.52
ISSN:1008-7664
年,卷(期):2024.26(3)
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