首页|中老年男性肌肉减少症与骨质疏松性骨折的相关性分析

中老年男性肌肉减少症与骨质疏松性骨折的相关性分析

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目的 探讨中老年男性肌肉减少症(SP)与骨质疏松症性骨折(OF)的相关性.方法 选取2020年2月至2023年2月中老年(50~70岁)男性骨质疏松症(OP)患者85例,其中OF 64例,非骨质疏松性骨折(NOF)21例.选取同期、同年龄段体检中心体检的非骨质疏松症患者(NOP)110例作为对照组.采用双能X线吸收骨密度仪(DXA)测量四肢骨骼肌肌肉量(ASM),计算出四肢骨骼肌指数(ASMI),观察6 m步行速度.分析中老年男性SP与OF的相关性.结果 OF组患者中SP患病率(71.88%)高于NOF组(61.90%),且高于NOP组(15.45%).SP组患者中,OP患病率(77.63%)高于NOP组(22.37%),其中OF患病率(77.97%)亦高于NOF组(22.03%).OP组患者ASM、ASMI、步行速度低于NOP组,其中OF组患者ASM、ASMI、步行速度低于NOF组,差异均有统计学意义(P<0.05).多因素分析显示,ASMI是OF的独立危险因素.结论 中老年男性SP患者易发生OP,且更易发生OF,预防OF对提高患者的生活质量,降低家庭和社会的经济负担有重要意义.
Objective To investigate the clinical relationship among sarcopenia(SP)and osteoporotic fractures(OF)in medium-elderly men patients.Methods Eighty-five patients among 50 to 70 years old with osteoporosis from February 2020 to February 2023 were enrolled in the study.Among them,64 patients were OF and 21 patients were non-OF(NOF).A total of 110 non-osteoporosis patients(NOP)who underwent physical examination in the same age group with the same exclusion criteria were selected as the control group.Appendicular skeletal muscle mass(ASM)was measured by dualenergy X-ray absorptiometry(DXA),and the appendicular skeletal muscle mass index(ASMI)was calculated.The daily walking speed was observed.Statistical software SPSS26.0 was used to process the data,and the results were recorded and analyzed.The correlation between SP and OF in medium-elderly men would be observed.Results The prevalence of SP in the OF group(71.88%)was higher than that in the NOF group(61.90%),and significantly higher than that in the NOP group(15.45%).The prevalence of OP(77.63%)in the SP group was significantly higher than that in the NOP group(22.37%),and the prevalence of OF(77.97%)was also significantly higher than in the NOF group(22.03%).The ASM,ASMI and the walking speed in the OP group were significantly lower than those in the NOP group.And besides,the ASM,ASMI and the walking speed in the OF group also were significantly lower than those in the NOF group,and the differences were statistically significant(P<0.05).Multivariate analysis showed that ASMI were independent risk factors of OF.Conclusion Middle aged and elderly male patients with SP are more prone to osteoporosis and OF.Preventing OF is very meaningful for improving the quality of life of patients and reducing the economic burden on families and society.

SarcopeniaOsteoporotic fracturesAppendicular skeletal muscle mass indexMedium-elderly men

刘振、叶春平、楼菁玲、刘叶美

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321000 浙江省金华市人民医院

321000 浙江省金华市文荣医院

241000 安徽芜湖华东师范大学附属芜湖医院(芜湖市第二人民医院)

肌肉减少症 骨质疏松性骨折 四肢骨骼肌指数 中老年男性

金华市科技计划

2020-4-047

2024

浙江临床医学
浙江中医药大学 浙江省科普作家协会医学卫生委员会

浙江临床医学

影响因子:0.52
ISSN:1008-7664
年,卷(期):2024.26(3)
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