Objective To observe the efficacy and safety of high-flow oxygen through nasopharyngeal airway(NPA)for painless electronic bronchoscopy(PLEB)in obese patients.Methods A total of fifty patients who were scheduled to undergo PLEB in the Affiliated Hospital of Jiaxing University from June 2021 to May 2023 were selected for this study.The patients were randomly divided into two groups(n=25)using the random number table method.The test group received high-flow oxygen through NPA,while the control group received high-flow oxygen through nasal cannula.Total intravenous anesthesia was administered for both the induction and maintenance of anesthesia.PLEB was performed once the patient's bispectral index(BIS)value dropped below 60 and eyelash reflex disappeared.PaO2,PaCO2,SpO2,heart rate(HR),and mean arterial pressure(MAP)were recorded at the time of admission(T0),immediately after the start of bronchoscopy(T1),10 min after the start of bronchoscopy(T2),and immediately after the end of bronchoscopy(T3).Additionally,the cross-sectional area of the gastric antrum was measured at T0 and T3.The adverse effects and complications were also documented.Results Compared to the control group,the test group exhibited higher PaO2 and lower PaCO2 levels at T1,T2,and T3.Additionally,the test group experienced less fluctuation in MAP and a lower incidence of hypoxemia(SpO2＜92％)during anesthesia.These differences were found to be statistically significant(P＜0.05).Conclusion High-flow oxygen through NPA can provide safe and effective ventilation support for obese patients receiving PLEB,and significantly improve oxygenation and reduce CO2 accumulation.Further clinical studies and promotion of this technique are warranted.
High flow oxygen therapyBronchoscopyObesityNasopharyngeal airway
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