Objective To observe the efficacy and safety of repetitive transcranial magnetic stimulation(rTMS)combined with acupuncture in children with Tic Disorder(TD).Methods A total of 60 children with TD who received treatment from June 2021 to June 2022 in the Department of Rehabilitation,Jiaxing Hospital of Traditional Chinese Medicine,Zhejiang University of Traditional Chinese Medicine were randomly divided into the control group(acupuncture)and the treatment group(rTMS+ acupuncture)for 8 weeks.Yale Global Tic Severity Scale(YGTSS)and Clinical Global Impression(CGI)were used to evaluate and analyze the efficacy before the treatment,at the end of the 4th week and the 8th week of the treatment.Adverse reactions in both groups were simultaneously monitored.Results The YGTSS scores in both groups were comparable before the treatment and at the end of the 4th week(P>0.05).However,by the end of the 8th week,the treatment group showed significantly lower scores than the control group(P<0.05).The treatment group exhibited an efficacy rate of 86.7%,compared to 60.0%in the control group.The incidence of adverse reactions in both groups was 10%.Conclusion rTMS combined with acupuncture is significantly better than the control group in the treatment of tic disorder in children,demonstrating a favorable safety profile.This approach holds promise for broader clinical application.
Repetitive transcranial magnetic stimulationAcupunctureTic DisorderClinical study
NETL
NSTL
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