Objective To investigate the clinical efficacy of breast regional perfusion operation for the treatment of refractory granulomatous lobular mastitis(RGLM).Methods A total of 137 patients with a histopathologically proven diagnosis of RGLM who received regional breast perfusion from June 2020 to June 2021 were retrospectively analyzed.Results Among 137 patients,132 underwent unilateral operation and 5 underwent bilateral operation simultaneously.The average unilateral operation time was(30±5)min,and the intraoperative bleeding loss was(60±18)mL.There were no ischemic necrosis nipple after surgery.The coexistence of RGLM,severe breast pain,erythema nodosum,arthritis,fever,dry cough,and headache resolved within 1 week.Patients were taken Yanghe decoction orally for(2.9±0.7)months after surgery.The average follow-up time was 23.5 months,and the recurrence rate was 0.7%.None of the 9 women who intended to breastfeed had lactation Mastitis within 6 months.All patients showed excellent results in the aesthetic evaluation of breast appearance.Conclusion Breast regional perfusion operation can safely and effectively treat RGLM,and the follow-up results show that the therapeutic effect has basically reached the expected goal.
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