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结直肠癌根治术后谵妄发生的影响因素分析

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目的 分析结直肠癌患者行根治手术术后谵妄(POD)的发生率及其相关影响因素。方法 回顾性分析2021年1月至2022年6月198例行结直肠癌根治术患者的临床资料。采用意识错乱评估法将术后患者分为POD组和非POD组。比较2组患者一般资料、疾病特征和手术资料,分析患者术后发生谵妄的相关危险因素。结果 28例患者术后出现谵妄。POD组患者年龄、饮酒、感染程度、剖腹手术、镇痛泵使用次数均高于非POD组,差异有统计学意义(P<0。05)。POD组患者文化程度、体力活动、营养状况均低于非POD组,差异有统计学意义(P<0。05)。多因素Logistic回归分析显示,术后活动不足(OR=2。84,P=0。001)、出现感染(OR=2。16,P=0。01)和营养状况差(OR=1。3,P=0。02)是POD发生的独立影响因素。结论 为了预防和减少结直肠癌患者POD的发生,患者术前应适当体育运动、术后尽快下床活动,并定期监测感染指标和营养状况,及时调整临床治疗及护理宣教方案。
Objective To analyze the incidence and related influencing factors of postoperative delirium(POD)in patients with colorectal cancer undergoing radical surgery.Methods A total of 198 patients who underwent radical surgery for colorectal cancer from January 2021 to June 2022 were selected as the research subjects.The postoperative patients were divided into a POD group and a non-POD group by using the consciousness disorder assessment method.The general information,disease characteristics,and surgical data of patients in two groups were compared,and the relevant risk factors for postoperative delirium in patients were analyzed.Results 28 patients experienced postoperative delirium.The age,alcohol consumption,degree of infection,number of laparotomy surgeries,and the use of analgesic pumps in the POD group were all higher than those in the non-POD group,with statistical differences(P<0.05).The education level,physical activity,and nutritional status of patients in the POD group were lower than those in the non-POD group,with statistical differences(P<0.05).The results of multivariate logistic regression analysis showed that insufficient postoperative activity(OR=2.84,P=0.001),infection(OR=2.16,P=0.01),and poor nutritional status(OR=1.3,P=0.02)were independent influencing factors for the occurrence of POD.Conclusion In order to prevent and reduce the occurrence of POD in colorectal cancer patients,it is necessary to require patients to exercise appropriately before surgery,get out of bed as soon as possible after surgery,regularly monitor infection indicators and nutritional status,and adjust clinical treatment and nursing education plans in a timely manner.

Colorectal cancerDeliriumNutritionInfectionInfluencing factors

朱伟国、朱聪

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313000 浙江省湖州市中心医院(浙江大学医学院附属湖州医院)

结直肠癌 谵妄 营养 感染 影响因素

2024

浙江临床医学
浙江中医药大学 浙江省科普作家协会医学卫生委员会

浙江临床医学

影响因子:0.52
ISSN:1008-7664
年,卷(期):2024.26(4)
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