浙江临床医学2024,Vol.26Issue(5) :669-672.

甘油三酯葡萄糖指数与接受PCI术的绝经后ACS患者预后的相关性分析

陈森江 周亮
浙江临床医学2024,Vol.26Issue(5) :669-672.

甘油三酯葡萄糖指数与接受PCI术的绝经后ACS患者预后的相关性分析

陈森江 1周亮2
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作者信息

  • 1. 310053 浙江中医药大学第四临床医学院
  • 2. 310003 杭州市第一人民医院
  • 折叠

摘要

目的 探讨甘油三酯葡萄糖指数对接受经皮冠状动脉介入术的绝经后妇女急性冠脉综合征患者预后的预测价值.方法 本研究共纳入313名行经皮冠状动脉介入治疗术的绝经后妇女急性冠脉综合征患者.根据是否发生主要心血管不良事件(MACE)分为无MACE组和MACE组,根据TyG指数四分数分为T1、T2、T3、T4组,对各组进行比较,评估TyG指数对接受PCI术绝经后妇女急性冠脉综合征患者远期预后的影响.采用多因素COX回归分析影响不良预后的因素,采用Kaplan-Meier曲线比较TyG各组之间的生存情况.结果 在随访中位时间4年的随访期间,共112(35.8%)例患者出现MACE事件,多因素COX回归分析显示甘油三酯葡萄糖指数是MACE的独立预测因子(HR=1.428,95%CI:1.031~1.979,P=0.032).Kaplan-Meier曲线和log-rank分析显示不同TyG组间生存率存在显著差异(P=0.034),且随TyG指数的增加而降低.结论 甘油三酯葡萄糖指数对接受PCI术的绝经后妇女急性冠脉综合征患者的远期预后具有一定的预测价值.

Abstract

Objective To investigate the prognostic value of triglyceride glucose(TyG)index in postmenopausal women with acute coronary syndrome(ACS)undergoing percutaneous coronary intervention(PCI).Methods A total of 313 postmenopausal women with ACS undergoing PCI were enrolled in this study.According to the occurrence of major cardiovascular adverse events(MACE),the two groups were divided into the non-MACE group and the MACE group,and the four groups were divided into T1,T2,T3 and T4 groups according to the quartiles of TyG index.To evaluate the effect of TyG index on the long term prognosis of postmenopausal women with ACS undergoing PCI.Multivariate COX regression was used to analyze the factors affecting the adverse prognosis,and the Kaplan-Meier curve was used to compare the survival among TyG groups.Results During a median follow-up of 4 years,112(35.8%)patients had MACE events.Multivariate COX regression analysis showed that triglyceride glucose index was an independent predictor of MACE(HR=1.428,95%CI:1.031~1.979,P=0.032).Kaplan-Meier curve and log-rank analysis showed that there were significant differences in survival rate among different TyG groups(P=0.034),and the survival rate decreased with the increase of TyG index.Conclusion Triglyceride glucose index has a certain predictive value for the long term prognosis of postmenopausal women with ACS undergoing PCI.

关键词

甘油三酯葡萄糖指数/急性冠脉综合征/绝经后妇女/PCI/预后

Key words

Triglyceride glucose index/Acute coronary syndrome/Postmenopausal women/PCI/Prognosis

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出版年

2024
浙江临床医学
浙江中医药大学 浙江省科普作家协会医学卫生委员会

浙江临床医学

影响因子:0.52
ISSN:1008-7664
参考文献量27
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