Objective To observe effect of upper cervical segments manipulative reduction and traction for the treatment of cervical greater occipital neuralgia,discuss the asymmetric grouping and precise management of cervical greater occipital neuralgia.Methods 108 patients with cervical greater occipital neuralgia were randomly divided into three groups according to the visiting orders:60 patients in group A treated upper cervical segments and upper cervical segments manipulative reduction and traction,60 patients in group B treated upper cervical segments,60 patients in group C treated cervical traction.Before and after treatment,we were calculated the visual analog scores(VAS)and assessed clinic therapeutic efficacy in the three groups.Results According the evaluation,there was the significantly different in group A to group B and C(P<0.05),the total effective rate in group A was 96.7%,88.3%in group B,and 76.7%in group C.The total effective rate of group A was significantly higher than the other two groups(P<0.05).And the effective rate of group B was higher than group C.Conclusion The treatment of upper cervical segments manipulative reduction and traction for cervical greater occipital neuralgia are better simple manipulative reduction or cervical traction,which has better precision and safety when locating and practicing and is easy to train.The asymmetric grouping are more conform to clinic.