Objective To explore the application value of radiofrequency ultrasound vascular measurement technique in quantitatively detecting carotid artery elasticity in young and middle-aged patients with type 2 diabetes mellitus(T2DM).Methods A total of 83 young and middle-aged patients aged 18~60 with T2DM were selected as the case group.Based on the presence or absence of carotid artery plaques,they were divided into the plaque group(Group A)and the non-plaque group(Group B).Additionally,40 age-matched healthy individuals were selected as the control group(Group C).General clinical data were collected from the three groups,and parameters related to carotid artery elasticity including intima-media thickness(IMT),arterial Distention Coefficient(DC),compliance coefficient(CC),stiffness index(α andβ),and pulse wave velocity(PWV)of the left carotid artery were recorded.Results In the T2DM group,the left carotid artery DC and CC were lower than those in the control group,while IMT,α,β,and PWV were significantly higher than those in the normal control group,with statistical significance(P<0.05).When comparing T2DM patients with and without plaques,IMT in group A was significantly thicker than that in the group B(P<0.05),while there was no statistically significant difference in PWV between the two subgroups(P>0.05).Additionally,a positive correlation was observed between carotid artery PWV and IMT in the T2DM group(P<0.05).Conclusion Radiofrequency ultrasound technology can accurately detect carotid artery IMT and PWV in young and middle-aged patients with T2DM.Moreover,PWV is more sensitive in assessing early-stage carotid artery elasticity decline in carotid artery stiffening,providing valuable guidance for early clinical prevention and treatment.