Objective To explore the changes in cognitive function and influencing factors during non-convulsive electroconvulsive therapy(mECT)in patients with depression.Method A convenience sampling method was used to investigate cognitive function in 209 patients with depression during MECT at 12 different time points(before treatment,before surgery,1 week and 2 weeks of acute phase,at the end of acute phase,1 week,2 weeks,4 weeks,6 weeks,8 weeks,12 weeks,and 16 weeks of maintenance phase)using the Cognitive Assessment Scale(MMSE).A curve of cognitive function change during mECT was drawn.Univariate analysis and multiple regression analysis on the cognitive function changes of patients during treatment was conducted.Results During the mECT period,the average score of the patient's cognitive function was 26.19±2.91.The low value of the patient's cognitive function occurred during the acute treatment period,and the cognitive function score was higher at the end of the entire treatment cycle than before the treatment.The influencing factors of cognitive function changes include the patient's age,course of disease,and degree of depression(P<0.05).Conclusion During the mECT period of depression patients,cognitive function showed a trend of high at both ends and low at the acute stage over time.Medical staff should implement personalized and targeted guidance based on the curve of cognitive function changes and influencing factors,alleviate the negative emotions of patients and their families,and thus improve the enthusiasm of mECT.
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