Objective To investigate the curative effect of ultrasound combined with balloon-guided injection of botulinum toxin A in treating dysphagia caused by cricopharyngeal achalasia after stroke.Methods From April 2021 to April 2023,32 patients with post-stroke cricopharyngeal achalasia were selected and divided into the routine swallowing training(control group)and the ultrasound combined with balloon-guided botulinum toxin A injection(observation group),with 16 patients in each group.After 4 weeks of treatment,the standard swallowing function scale(SSA),dysphagia angiographic assessment scale(VDS)and swallowing-related quality of life(SWAL-QOL)questionnaire were used to evaluate the clinical efficacy of the patients.Results The total effective rate was 87.5%(14/16)in the observation group and 68.8%(11/16)in the control group.There was significant difference in the total effective rate between the two groups(P<0.05).After treatment,the dysphagia score and swallowing related quality of life score of all patients were improved.In addition,the improvement values of SSA score,VDS score and SWAL-QOL score in the observation group were better than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The implementation of ultrasound combined with balloon guided injection of botulinum toxin A on the basis of routine swallowing training is effective,safe,and convenient for the treatment of post stroke cricopharyngeal muscle achalasia,and is worthy of clinical promotion and application.