超声联合球囊引导下注射A型肉毒毒素治疗脑卒中后环咽肌失弛缓症疗效
吴登宠 1陈佳君 1朱烈烈1
作者信息
- 1. 325000 浙江中医药大学附属温州市中医院
- 折叠
摘要
目的 观察超声联合球囊引导下注射A型肉毒毒素(BTX-A)治疗脑卒中后环咽肌失弛缓症(CPA)的疗效.方法 选取2021年4月至2023年4月脑卒中后CPA患者32例,将患者分为2组进行训练,对照组接受常规吞咽训练;观察组在常规吞咽训练的基础上采用超声联合球囊引导下注射BTX-A,每组各16例.治疗4周后,两组均采用标准吞咽功能评分量表(SSA)、吞咽障碍造影评估量表(VDS)和吞咽相关生活质量(SWAL-QOL)调查问卷评价患者的疗效.这些评估工具可以帮助我们了解患者的吞咽功能、吞咽障碍程度以及对生活质量的影响.结果 观察组总有效率87.5%,对照组总有效率68.8%,两组比较差异有统计学意义(P<0.05).治疗后,患者吞咽障碍评分和吞咽相关生活质量评分均有改善.观察组SSA评分、VDS评分和SWAL-QOL评分改善优于对照组,差异有统计学意义(P<0.05).结论 在常规吞咽训练基础上实施超声联合球囊引导下注射BTX-A治疗卒中后CPA疗效确切,安全简便,值得临床推广应用.
Abstract
Objective To investigate the curative effect of ultrasound combined with balloon-guided injection of botulinum toxin A in treating dysphagia caused by cricopharyngeal achalasia after stroke.Methods From April 2021 to April 2023,32 patients with post-stroke cricopharyngeal achalasia were selected and divided into the routine swallowing training(control group)and the ultrasound combined with balloon-guided botulinum toxin A injection(observation group),with 16 patients in each group.After 4 weeks of treatment,the standard swallowing function scale(SSA),dysphagia angiographic assessment scale(VDS)and swallowing-related quality of life(SWAL-QOL)questionnaire were used to evaluate the clinical efficacy of the patients.Results The total effective rate was 87.5%(14/16)in the observation group and 68.8%(11/16)in the control group.There was significant difference in the total effective rate between the two groups(P<0.05).After treatment,the dysphagia score and swallowing related quality of life score of all patients were improved.In addition,the improvement values of SSA score,VDS score and SWAL-QOL score in the observation group were better than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The implementation of ultrasound combined with balloon guided injection of botulinum toxin A on the basis of routine swallowing training is effective,safe,and convenient for the treatment of post stroke cricopharyngeal muscle achalasia,and is worthy of clinical promotion and application.
关键词
环咽肌失弛缓/肉毒毒素A/超声引导/球囊/卒中Key words
Cricopharyngeal achalasia/Botulinum toxin A/Ultrasound/Balloon/Stroke引用本文复制引用
出版年
2024
NETL
NSTL
万方数据