Objective To analyze influencing factors of early tracheal extubation after operation of ventricular septal defect(VSD)in children.Methods The clinical data of 102 children who underwent VSD repair in our hospital from June 2020 to May 2022 were retrospectively analyzed.The children were divided into early extubation group(≤8 h)and non-early extubation group(>8 h)according to the time of postoperative extubation.The differences of preoperative,intraoperative and postoperative factors between the two groups were compared.The possible influencing factors were included in the multivariate Logistic regression model for analysis,and the independent risk factors affecting early extubation were finally identified.Results A total of 102 children with VSD were enrolled,including 66 cases in the early postoperative extubation group and 36 cases in the non-early postoperative extubation group.The univariate analysis demonstrated that age,body weight,preoperative severe pulmonary hypertension,diameter size of VSD,operation time,cardiopulmonary bypass time,aortic occlusion clamping time,postoperative low cardiac output syndrome were associated with early tracheal extubation after operation of VSD in children(P<0.05).The multivariate logistics regression analysis demonstrated that preoperative severe pulmonary hypertension,operation time,cardiopulmonary bypass time,aortic occlusion clamping time,postoperative low cardiac output syndrome were significantly associated with early tracheal extubation.Conclusion Early removal of tracheal intubation in children with ventricular septal defect after surgery is safe and feasible.Preoperative severe pulmonary hypertension,operation time,cardiopulmonary bypass time,aortic occlusion clamping time,postoperative low cardiac output syndrome are the main influencing factors of early tracheal extubation after operation of VSD in children.
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