Objective To evaluate the short-term prognosis of patients with acute ischemic stroke with middle cerebral artery occlusion(AIS-MCAO)using the ratio of Hounsfield unit(HU)variance.Methods A total of 73 patients with AIS-MCAO confirmed using CTA were enrolled.According to the modified Rankin score(mRS)at 90 days,patients were divided into a good prognosis group(42 patients)and a poor prognosis group(31 patients).Logistic regression analysis was used to analyze the factors affecting the prognosis of patients with AIS-MCAO.A receiver operating characteristic(ROC)curve was used to determine the predictive value of rHUV for the short-term prognosis of patients with AIS-MCAO.Results The rHUV was independent risk factor for prognosis(P<0.05).The area under the ROC curve of the rHUV was 0.887.The Youden index of rHUV in the ROC curve was 0.694,with an optimal critical point of 0.675,indicating that rHUV<0.675 was associated with a poor prognosis,whereas rHUV>0.675 indicated a good prognosis.Conclusion We established a simple algorithm,rHUV,that could effectively evaluate the short-term prognosis of patients with AIS-MCAO.
CTAAcute ischemic stroke with middle cerebral artery occlusionAlberta Stroke Program Early CT ScoreModified Rankin score
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