Objective To explore the risk factors of aspiration pneumonia in patients with acute ischemic stroke during hospitalization,and to construct a prediction model for the risk of aspiration pneumonia in patients with acute ischemic stroke during hospitalization.Methods The clinical data of patients admitted for acute ischemic stroke in The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University were collected,such as demographic data,laboratory examination,vital signs etc.The risk factors of aspiration pneumonia were screened out by univariate and multivariate Logistic regression analysis,and a predictive model was established.Results Advanced age,low GCS score on admission,history of stroke,history of diabetes,dysphagia and hypoalbuminemia were risk factors for aspiration pneumonia in patients with acute ischemic stroke.The area under the ROC curve(AUC)of the prediction model for the risk of aspiration pneumonia was 0.831(0.786~0.876),and the AUC for internal verification to predict the risk of aspiration pneumonia was 0.827(0.782~0.873).Hosmer-Lemeshow test:χ2=12.585,P=0.127.Conclusion This predictive model is in favor of clinicians to evaluate the risk of aspiration pneumonia during hospitalization in patients with acute ischemic stroke,with good discrimination and calibration.
Acute ischemic strokeAspiration pneumoniaScore of prediction