Objective To collect the clinical characteristics,inflammatory indicators and treatment of patients with Nocardia infections,and to provide a basis for early identification and prevention of the disease.Methods The clinical data of 39 patients with Nocardiosis from 2018 to 2023 were retrospectively analyzed,laboratory infection indexes,etiological characteristics and treatment were collected and analysed.Results Of the 39 patients with Nocardia infection,36 cases were combined with underlying diseases.There were 24 cases of respiratory system infection,11 cases of skin infection,2 cases of systemic disseminated infection,and 1 case each of urinary tract infections and lymphadenitis.The distribution of infectious organisms was Nocardia brasiliensis in 11 cases,Nocardia farcinica,Nocardia cyriacigeorgica,and Nocardia otitidiscaviarum in 7 cases,Nocardia beijingensis in 2 cases,Nocardia neocaledoniensis in 1 case,Nocardia wallacei in 1 case,and unclassified Nocardia in 3 cases.The proportion of patients with elevated laboratory inflammatory index C-reactive protein was the highest,accounting for 79.41% .The clinical treatment plan was based on the combination of compound sulfamethoxazole,and the cure rate of patients was high.Conclusion The Nocardiae can cause systemic multi-site infection,and the infection rate is higher in patients with underlying diseases.Different strains of Nocardia cause different sites of infection,clinical manifestations and inflammatory indicators,and the therapeutic effects of different strains are also quite different.Therefore,the appropriate treatment plan should be selected according to the laboratory test results.
万方数据
维普
