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加味半夏泻心汤治疗稳定性冠心病的疗效观察

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目的 基于气机升降理论探讨加味半夏泻心汤对稳定性冠心病(SCAD)患者的疗效.方法 选取2021年3月至2023年9月SCAD患者60例,按随机数字法分为对照组和观察组,各30例.对照组给予常规西药治疗,观察组在对照组基础上给予加味半夏泻心汤治疗,比较两组心绞痛积分、心肌耗氧量、生活质量评分、心电图改善和心绞痛治疗有效率、超敏C-反应蛋白(hs-CRP)、一氧化氮(NO)、同型半胱氨酸(Hcy)、内皮素(ET-1)水平.结果 两组治疗后心绞痛积分、心肌耗氧量、hs-CRP、Hcy、ET-1水平、生活质量评分与治疗前比较差异有统计学意义(P<0.05).治疗后,两组心绞痛积分、hs-CRP、Hcy、ET-1水平、生活质量评分、心电图改善和心绞痛治疗有效率比较差异有统计学意义(P<0.05).结论 加味半夏泻心汤可以缓解SCAD患者心绞痛,降低心肌耗氧量,提高疗效,改善患者生存质量,促进患者内皮功能恢复.
Objective To study the clinical observation of Modified Banxia Xiexin Decoction on Stable Coronary Heart Disease Based on the Theory of Qi Movement Upregulation.Methods Sixty patients with Stable coronary heart disease were selected.They were randomly divided into two groups that contains a control group and an observation group,with 30 cases in each group.The control group was given routine Western medicine treatment,and the observation group was treated with modified Banxia Xiexin Decoction on the basis of the control group's treatment.The angina score,myocardial oxygen consumption,electrocardiogram treatment and angina treatment efficiency were compared,the quality of life,and the levels of hs-CRP,NO,Hcy and ET-1 between the two groups were evaluated.Results The differences in the scores of angina pectoris,myocardial oxygen consumption,hs-CRP,Hcy,ET-1,and the scores of PL,AS,AF and TS were statistically significant when compared between the two groups before and after the treatment(P<0.05).After the treatment,the differences in the scores of angina pectoris,hs-CRP,Hcy,ET-1,the scores of PL,AS,AF and TS and the effective rate of ECG improvement and angina pectoris were statistically significant when compared between the two groups(P<0.05).Conclusion Modified Banxia Xiexin Decoction can relieve angina pectoris in patients with stable coronary heart disease,reduce myocardial oxygen consumption,improve the efficacy of electrocardiogram,improve the quality of life of patients,a nd promote the recovery of endothelial function.

Modified Banxia Xiexin DecoctionTheory of pneumatic lifting and loweringStable coronary heart diseaseEndothelial functionQuality of life

吴山永、褚振亮、张裕惠、陈韦伽、俞沛文、沈维、杨慧婷、赵圣刚、姜宁华

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314000 嘉兴大学附属第二医院

加味半夏泻心汤 气机升降理论 稳定性冠心病 内皮功能 生活质量

2024

浙江临床医学
浙江中医药大学 浙江省科普作家协会医学卫生委员会

浙江临床医学

影响因子:0.52
ISSN:1008-7664
年,卷(期):2024.26(7)