Objective To explore the risk factors that may lead to poor prognosis of cerebral hemorrhage with hematologic coagulopathy cerebral hemorrhage.Methods The clinical data of 39 patients with cerebral hemorrhage of coagulation dysfunction in hematological diseases were retrospectively analyzed,grouped according to hematological diseases,and age of onset,gender,clinical symptoms at admission,blood pressure,consciousness,bleeding site,and coagulation indexes of the patients were collected to analyze the risk factors of poor prognosis of cerebral hemorrhage.Results Logistic regression analysis of NIHSS score(95% CI:1.24～3.18,P<0.05),degree of disturbance of consciousness(95% CI:5.47～217.19,P<0.001),dizziness and fatigue symptoms(95% CI:0.03～0.67,P<0.05),headache and nausea(95% CI:0.06～1.00,P<0.05)were risk factors for poor prognosis in patients with cerebral hemorrhage with blood disease coagulation disorder.The prothrombin time(PT)was significantly longer and the international normalized ratio(INR)was significantly higher in leukemia group(P<0.05).There was a correlation between different bleeding sites and prolonged PT,elevated total leukocyte count,PT INR and D-dimer(P<0.05).Conclusion The NIHSS score,the degree of consciousness disturbance,dizziness,fatigue,headache and nausea at onset can predict the poor prognosis of the patients.Among the different hematological conditions,the leukemia group had the worst prognosis.
CoagulopathyCerebral hemorrhageClinical featuresRisk factorsImaging features
万方数据
维普
