Objective To explore and analyze the predictive value of joint detection of fracture duration,plasma D-dimer(D-D),and fibrinogen degradation products(FDP)for lower limb deep vein thrombosis(DVT)in patients with proximal femoral fractures.Methods Retrospective analysis was performed for 241 aged patients with proximal femoral fractures from January 2023 to June 2023,including 117 males and 124 females,with 80 healthy people who underwent health examinations during the same period served as the control group.Continuous dynamic monitoring of plasma D-D and FDP levels before and after surgery together with the duration of fractures,were statistically analyzed the predictive value of occurrence of lower limb DVT.Results The results showed that the postoperative plasma D-D and FDP levels in the observation group were higher than those in the control group(P<0.05).Within the observation group,the postoperative plasma D-D and FDP levels in patients with DVT were higher than those without DVT(P<0.05).The longer the duration of fracture,the higher the risk of lower limb DVT for postoperative patients(P<0.05).Conclusion Continuous dynamic detections of FDP and D-D can closely monitor the coagulation and fibrinolysis status in the body with the duration of fracture as a risk factor for lower limb DVT,which is helpful for the early diagnosis of DVT in postoperative patients with fractures.