摘要
目的 分析脑小血管病(CSVD)与甲状腺功能的相关性.方法 收集2020年5月至2022年11月71例脑小血管病患者的临床资料(CSVD组).同期健康体检的71例患者为对照组.分析两组患者甲状腺功能指标(TT3、TT4、FT3、FT4、TSH、TgAb、TPOAb、Tg、TRAb)的差异.结果 两组年龄、吸烟、高血压、糖尿病、高同型半胱氨酸血症、高尿酸血症、TT3、FT3、FT4、TSH、TRAb差异有统计学意义(P<0.05).多因素Logistic回归分析结果显示,FT3、TSH、高同型半胱氨酸血症、年龄是CSVD的影响因素(P<0.05).FT3是CSVD的保护性因素,TSH是CSVD的危险因素.结论 CSVD与甲状腺激素FT3及TSH存在相关性.建议CSVD患者检测甲状腺激素,重点关注FT3及TSH水平.
Abstract
Objective To analyze the correlation between cerebral small vessel disease(CSVD)and thyroid function.Methods 71 patients with cerebral small vessel disease from May 2020 to November 2022 were selected into the CSVD group.71 patients who underwent health checkups during the same period were selected as the control group.The differences in thyroid function indicators(TT3,TT4,FT3,FT4,TSH,TgAb,TPOAb,Tg,TRAb)between two groups of patients were analyzed.Results There were significant differences in age,smoking,hypertension,diabetes,hyperhomocysteinemia,hyperuricemia,TT3,FT3,FT4,TSH,and TRAb between the two groups(P<0.05).The results of multiple Logistic regression analysis showed that FT3,TSH,hyperhomocysteinemia and age were correlated with CSVD(P<0.05).FT3 is a protective factor for CSVD.TSH is a risk factor for CSVD.Conclusion There was a correlation between CSVD and thyroid hormones FT3 and TSH.It is recommended that CSVD patients undergo thyroid hormone testing,with a focus on FT3 and TSH levels.
维普
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