首页|脑小血管病与甲状腺激素的相关性分析

脑小血管病与甲状腺激素的相关性分析

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目的 分析脑小血管病(CSVD)与甲状腺功能的相关性。方法 收集2020年5月至2022年11月71例脑小血管病患者的临床资料(CSVD组)。同期健康体检的71例患者为对照组。分析两组患者甲状腺功能指标(TT3、TT4、FT3、FT4、TSH、TgAb、TPOAb、Tg、TRAb)的差异。结果 两组年龄、吸烟、高血压、糖尿病、高同型半胱氨酸血症、高尿酸血症、TT3、FT3、FT4、TSH、TRAb差异有统计学意义(P<0。05)。多因素Logistic回归分析结果显示,FT3、TSH、高同型半胱氨酸血症、年龄是CSVD的影响因素(P<0。05)。FT3是CSVD的保护性因素,TSH是CSVD的危险因素。结论 CSVD与甲状腺激素FT3及TSH存在相关性。建议CSVD患者检测甲状腺激素,重点关注FT3及TSH水平。
Objective To analyze the correlation between cerebral small vessel disease(CSVD)and thyroid function.Methods 71 patients with cerebral small vessel disease from May 2020 to November 2022 were selected into the CSVD group.71 patients who underwent health checkups during the same period were selected as the control group.The differences in thyroid function indicators(TT3,TT4,FT3,FT4,TSH,TgAb,TPOAb,Tg,TRAb)between two groups of patients were analyzed.Results There were significant differences in age,smoking,hypertension,diabetes,hyperhomocysteinemia,hyperuricemia,TT3,FT3,FT4,TSH,and TRAb between the two groups(P<0.05).The results of multiple Logistic regression analysis showed that FT3,TSH,hyperhomocysteinemia and age were correlated with CSVD(P<0.05).FT3 is a protective factor for CSVD.TSH is a risk factor for CSVD.Conclusion There was a correlation between CSVD and thyroid hormones FT3 and TSH.It is recommended that CSVD patients undergo thyroid hormone testing,with a focus on FT3 and TSH levels.

Cerebral small vessel diseaseHypothyroidismFT3TSH

陈媚娇、陈煜阳、许佳颖、叶玲琪、裘涛

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310003 浙江中医药大学附属第一医院

318000 浙江省天台县人民医院

310009 浙江大学医学院附属第二医院

脑小血管病 甲状腺功能减退 游离三碘甲状腺原氨酸 促甲状腺激素

2024

浙江临床医学
浙江中医药大学 浙江省科普作家协会医学卫生委员会

浙江临床医学

影响因子:0.52
ISSN:1008-7664
年,卷(期):2024.26(8)