Objective To evaluate the effect of prostate cancer screening in high-risk groups.Methods A total of 582 patients over 60 years old with serum PSA>4μg/L were selected from prostate cancer screening bases(screening group)in Zhuji City,Zhejiang Province and Zhuji People's Hospital(outpatient group)from January 2020 to December 2022 for prostate biopsy.The positive rate of prostate cancer and the risk factors of prostate cancer were compared between the screening group and the outpatient group.Results Comparison of prostate cancer positivity rates between patients in the screening and outpatient groups showed no statistically significant difference(χ2=3.038,P=0.081).The detection rate of high-risk prostate cancer in screening group was significantly lower than that in outpatient group(P<0.05).Comparison of PSA levels,Gleason scores and clinical stages of patients diagnosed with prostate cancer in the two groups showed statistically significant differences(P<0.05).Conclusion Screening for prostate cancer in high-risk groups can effectively improve the detection rate of low-risk and medium-risk prostate cancer patients.Strengthening the health education for patients with abnormal PSA is conducive to the smooth development of prostate cancer screening.
关键词
前列腺癌筛查/前列腺特异性抗原/前列腺穿刺
Key words
Prostate cancer screening/Prostate-specific antigen/Prostatic puncture
维普
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