Objective To explore the relationship between the degree of depression and exercise related factors in patients with depressive disorder.Methods A random sampling method was used to select 200 patients with MDD from March to September 2022 to collect data on patients'age,gender,exercise-related factors,and depression severity,and to analyze the relationship between depression severity and exercise-related factors.Results There were significant differences in sleep duration,exercise frequency,anxiety somatization and block factor between patients with and without exercise supervision(P<0.05).There were significant differences in sleep duration,exercise frequency,anxiety somatization,block and sleep disorder factors among depressive patients with different heart rate during exercise(P<0.05).The linear regression results of depression degree and exercise related factors showed that exercise duration was a risk factor for depression degree,and exercise frequency and intensity were protective factors for depression degree.Conclusion Correlation between depression severity and exercise-related factors in patients with MDD,exercise may be an effective way to combat depressive disorders.