Objective To analyze the characteristics and risk factors of pulmonary infection in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)and type Ⅱ respiratory failure after mechanical ventilation,so as to provide a basis for the clinical diagnosis and treatment of patients with mechanical ventilation and the prevention of pulmonary infection.Methods The clinical data of 368 patients with AECOPD combined with type Ⅱ respiratory failure were retrospectively analyzed from January 2021 to November 2022,and the presence or absence of pulmonary infections after mechanical ventilation treatment was divided into group A(159 cases in the infected group)and group B(209 cases in the uninfected group),to analyze the probability that the patients suffered from pulmonary infections and the risk factors that triggered the pulmonary infections.Results 159 cases(43.21％)in the study for the presence of pulmonary infections and a total of 178 pathogenic bacteria were isolated from their sputum or secretion cultures.Multifactorial regression analysis showed that age≥65 years,rural residence,those with chronic smoking behavior and three or more underlying diseases in the organism,incision of the trachea,more than 5 days of mechanical ventilation,presence of invasive procedures,and more frequent aspiration were risk factors for the development of lung infections.Conclusion When AECOPD and type Ⅱ respiratory failure are combined,the risk of pulmonary infection can be increased under the influence of various factors such as underlying diseases and smoking,and targeted countermeasures should be taken in clinical diagnosis and treatment to minimize the risk of pulmonary infection.
万方数据
维普
