Objective To investigate the effect of gamma globulin on neutrophil/lymphocyte ratio(NLR),procalcitonin(PCT),C-reactive protein(CRP)in patients with novel coronavirus(COVID-19)pneumonia.Methods Select 80 hospitalized patients with COVID-19 infection in our hospital from December 2022 to February 2023,and randomly divide them into a control group and an observation group,with 40 patients in each group.Both groups of patients received symptomatic treatment including antiviral therapy,early anticoagulation,corticosteroid anti-inflammatory therapy,and oxygen therapy according to the standard treatment plan.The observation group received intravenous injection of human immunoglobulin needles in addition to the control group,and was treated synchronously for 5 days.Dynamically monitor the changes in blood routine,PCT,CRP,and other infection indicators during the treatment period of two groups,and dynamically monitor arterial blood gas and lung imaging to evaluate infection control and adverse reaction occurrence.Results Compared with before treatment,the values of NLR,PCT,and CRP in both groups of patients decreased significantly(P＜0.05).After treatment,the observation group showed a more significant decrease in NLR values compared to the control group,with a statistically significant difference(P＜0.05).There was no statistically significant difference in the decrease of PCT and CRP values.Conclusion Gamma globulin can reduce the NLR of patients with COVID-19 pneumonia,which is helpful to improve the patient's condition.
万方数据
维普
