Objective To explore the application value of thromboelastography(TEG)in assessing the coagulation function of patients with gynecological malignant tumors in the perioperative period and in predicting the occurrence of thrombosis.Methods A total of 70 patients with gynecological malignant tumors treated in our hospital in 2023 were selected as the observation group,and 60 healthy females who underwent physical examination served as the control group.Both groups underwent routine coagulation and TEG testing,and the results were compared and analyzed. Results There was no difference in basic information between the two groups.Except for activated partial thromboplastin time(APTT),the prothrombin time(PT),fibrinogen(FIB),D-dimer,R value,K value,Angle,and MA value of the observation group one day before surgery were significantly different from the control group(P<0.05).In addition,compared with before surgery,the routine coagulation test results and TEG test values of the observation group after surgery also showed significant differences(P<0.05).Within the observation group,there was no significant difference in PT and APTT between patients with stages Ⅲ and Ⅳ tumors and those with stages Ⅰ and Ⅱ,but there were significant differences in FIB,D-dimer,R value,K value,Angle,and MA value(P<0.05). In terms of surgical methods,there were significant differences in PT,FIB,D-dimer,and TEG test values of R value,K value,Angle,and MA value between the 20 patients who underwent parotomy and the 50 patients who underwent laparoscopic surgery(P<0.05).In the observation group,4 patients developed lower extremity venous thrombosis.In routine coagulation testing,except for D-dimer,the differences in other indicators compared with the 66 patients who did not develop thrombosis were not statistically significant,while the R value,K value,Angle,and MA value of TEG testing had significant differences(P<0.05). Conclusion Compared with routine coagulation testing,TEG can more accurately assess the coagulation function of patients with gynecological malignant tumors and effectively predict the occurrence of thrombosis.
ThromboelastographyCoagulation functionThrombosisMalignant tumorsGynecologyPerioperative period
万方数据
维普
