Objective To explore the application value of magnetic resonance imaging(MRI)susceptibility weighted imaging(SWI)in the differential diagnosis of primary Parkinson's disease(PD)and vascular parkinsonism(VP).Methods A retrospective analysis was conducted on 30 patients with primary PD and 30 patients with VP admitted to our hospital from June 2020 to June 2022.Additionally,30 healthy individuals who underwent physical examination during the same period were included as a control group.All subjects underwent MRI SWI scanning,and the width of the substantia nigra pars compacta(WPCSN),midbrain diameter,and the ratio of WPCSN to midbrain diameter were measured.The presence or absence of the "swallow-tail sign" in the dorsal lateral part of the substantia nigra was observed to assess its application value in differentiating PD and VP.Results The WPCSN and the ratio of WPCSN to midbrain diameter in the PD group were significantly smaller than those in the VP group and the control group(P<0.05).The WPCSN and the ratio of WPCSN to midbrain diameter in the VP group were also smaller than those in the control group(P<0.05).However,there was no significant difference in midbrain diameter among the three groups(P>0.05).Among PD patients,the "swallow-tail sign" was absent in 26 cases,and in VP patients,it was absent in 9 cases.The chi-square test showed that the difference was statistically significant(P<0.05).Conclusion MRI SWI shows certain clinical application value in differentiating PD from VP.
万方数据
维普
