Objective To explore the efficacy of selective music combined with repetitive transcranial magnetic stimulation(rTMS)in promoting the awakening of patients in a vegetative state(VS)and minimally conscious state(MCS)following traumatic brain injury(TBI).Methods A total of 69 TBI patients were selected,including 36 VS patients and 33 MCS patients.They were randomly assigned into three groups for VS patients(A1,B1,C1)and three groups for MCS patients(A2,B2,C2),with 12 and 11 patients in each group,respectively.Different treatment plans were designed:Group A(A1+A2) received conventional rehabilitation therapy,Group B(B1+B2)received conventional rehabilitation therapy plus rTMS stimulation,and Group C(C1+C2) received conventional rehabilitation therapy plus rTMS stimulation plus selective music therapy,with 23 cases in each group.The Glasgow Coma Scale(GCS) and Coma Recovery Scale-Revised(CRS-R)scores before and after treatment were compared to evaluate the therapeutic effect.Results After 4 weeks of treatment,there was a significant increase in GCS and CRS-R scores in all groups(P<0.01).The improvement in GCS scores in Groups B and C was significantly higher than that in Group A(P<0.01),and the improvement in CRS-R scores was also significantly higher than that in Group A(P<0.05).Similar therapeutic effects were observed in both VS patients(A1,B1,C1)and MCS patients(A2,B2,C2),with B1,B2,and C1,C2 groups showing significantly higher improvements in GCS and CRS-R scores than the corresponding A1,A2 groups(P<0.05 or P<0.01).Conclusion The combined treatment of selective music and rTMS is significantly effective in promoting the awakening of VS and MCS patients after TBI.This combined treatment plan is not only simple but also safe with minimal side effects,making it worthy of widespread application in clinical practice,offering new treatment options for VS and MCS patients after TBI.
Traumatic brain injuryConsciousnessVegetative stateMinimally conscious stateSelective music therapyRepetitive transcranial magnetic stimulation
万方数据
维普
