Objective To investigate the impact of 30％ and 80％ inspired oxygen concentration(FiO2)on postoperative complications in elderly patients undergoing elective laparoscopic abdominal surgery.Methods A total of 66 elderly patients,aged ≥65 years,with American society of anesthesiologists (ASA) classification of Ⅰ,Ⅱ,or Ⅲ,and an expected surgical or anesthesia time of ≥2 hours,were selected.Patients were randomly divided into two groups:the 30％ FiO2 group(Group A)and the 80％ FiO2 group(Group B).General conditions of the patients were recorded,and the highest values of N-terminal pro-B-type natriuretic peptide(NT-proBNP)concentration before and after surgery(2 hours,24 hours,and 48 hours),the incidence of myocardial injury after non-cardiac surgery(MINS),the incidence of postoperative complications within 7 days(PPCs),and the highest values of creatinine concentration before and after surgery(2 hours,24 hours,and 48 hours)were compared between the two groups.Additionally,postoperative incision infection,nausea and vomiting,heart failure,myocardial infarction,and new-onset arrhythmia within 30 days after surgery were recorded.Results There were no statistically significant differences in the highest values of NT-proBNP concentration before and after surgery,the incidence of MINS,renal function protection,and postoperative incision infection between the two groups(P>0.05).However,there was a statistically significant difference in the incidence of PPCs(atelectasis,pulmonary infection,pleural effusion,pneumothorax,respiratory failure,etc.)(P<0.05).Conclusion The use of 30％ FiO2 during surgery may have potential benefits in reducing the incidence of PPCs in elderly patients undergoing elective laparoscopic abdominal surgery.
Inspired oxygen concentrationIncidence of myocardial injury after non-cardiac surgeryN-terminal pro-B-type natriuretic peptideIncidence of postoperative complicationsElderly patients
万方数据
维普
