Post-stroke cognitive impairment is commonly seen in clinic.Electro-acupuncture(EA)can effectively improve the degree of post-stroke cognitive impairment and delay the development of cognitive impairment to dementia.Recently,with deepen study of the mechanism of EA in treatment of post-stroke cognitive impairment,synaptic plasticity,as a new starting point,provides a new idea for the study of the mechanism of EA in treating the disease.As an important part of brain plasticity,synaptic plasticity plays a vital role in nervous system activity,which is of great significance for the study of the mechanism of EA.Combing the relevant literature in recent years,the research progress of EA regulating synaptic plasticity in treatment of post-stroke cognitive impairment was explored from five aspects,including synaptic structural plasticity,synaptic functional plasticity,expression of synaptic plasticity related proteins,neurotransmitters and receptors,and synaptic plasticity related signal pathways.
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