Rule of Acupoints Selection in Treatment of POF Based on Data Mining
Objective:To analyze the rule of acupoints selection in treatment of premature ovarian failure(POF)based on data mining,and to explore the idea of using high-frequency core acupoints and the pathogenesis.Methods:The key words of'premature ovarian failure','acupuncture','acupuncture and moxibustion','electro-acupuncture','needle-warming moxibustion','moxibustion',and'combination of acupuncture and medication'were used to screen relevant literature about the treatment of POF from the databases of CNKI,Wanfang and VIP.The acupuncture prescriptions were recorded and sorted out,and the descriptive analysis,cluster analysis and correlation analysis of acupoints were carried out by using data mining technology.Results:A total of 67 pieces of literature meeting the criteria were selected and 91 sets of acupoint prescriptions were concluded.The top 5 acupoints frequently used in treatment of POF were Guanyuan(RN4),Sanyinjiao(SP6),Shenshu(BL23),Zusanli(ST36)and Zigong(EX-CA1).The most commonly involved meridians were Foot Taiyang Bladder Meridian,Ren Channel and Foot Taiyin Spleen Meridian.In terms of specific points,the main points were confluent points(239 times),front-Mu points(116 times),back-Shu points(110 times)and five-Shu points(107 times).The closest point pairs obtained by association rule analysis were RN4 → SP6,SP6 → ST36 and RN4 → ST36.Through cluster analysis,three kinds of prescriptions were obtained,including Shenting(DU24),Benshen(GB13),Baihui(DU20),Zhongwan(RN12),Luanchao,Tianshu(ST25),Dahe(KI12),Taixi(KI3),Taichong(LR3),ST36,Xuehai(SP10),Guilai(ST29),Zhongji(RN3)and Qihai(RN6);Pishu(BL20),Ganshu(BL18),Mingmen(DU4),BL23 and Ciliao(BL32);RN4,SP6 and EX-CA1.Conclusion:The treatment of POF by acupuncture and moxibustion is mainly to supplement Kidney-essence,assisted by regulating Liver and nourishing Heart,soothing Liver and strengthening Spleen.
Premature ovarian failureAcupuncture and moxibustionData miningRule of points selection