Influence of Tongue Acupuncture Combined with Body Acupuncture to Sex Hormone Levels and Sleep Quality in Patients with Perimenopausal Insomnia:A Randomized Controlled Trial
Objective:To compare the clinical efficacy of tongue acupuncture combined with body acupuncture and conventional acupuncture in treatment of perimenopausal insomnia and their influence to serum sex hormones.Methods:A total of 60 patients with perimenopausal insomnia were randomly divided into the observation group(n=30)and the control group(n=30).The control group was treated with conventional acupuncture,whereas the observation group was treated with tongue acupuncture combined with body acupuncture.Both groups were treated once a day for 4 courses of 20 days,with a two-day interval between the courses.At the end,one case dropped off in the observation group and two cases dropped off in the control group.The scores of Pittsburgh sleep quality index(PSQI)and domestic modified Kupperman scale,as well as the serum levels of estradiol(E2),luteinizing hormone(LH)and follicle stimulating hormone(FSH)were observed before the treatment,at the end of the treatment and one month after the treatment.Clinical efficacy was compared between the two groups.Results:After the treatment,sleep quality and the symptoms of perimenopausal syndrome were significantly improved after the treatment compared with those before the treatment(P＜0.05);the improvements were more significant in the observation group than those in the control group after the treatment and during the follow-up(P＜0.05).The level of E2 was increased,and the serum levels of LH and FSH were decreased after the treatment than those before the treatment in the two groups(P＜0.05);of which the improvements were more significant in the observation group than those in the control group(P＜0.05).Conclusion:Tongue acupuncture combined with body acupuncture can effectively improve sleep quality of patients with perimenopausal insomnia and other symptoms and signs of perimenopausal syndrome,it can improve life quality of the patients.The curative effect of the therapy is better than that of the conventional acupuncture.The mechanism may be related to regulating serum sex hormone levels,promoting adaption to fluctuations of perimenopausal sex hormones,and improving sleep rhythm and sleep quality.
万方数据
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