Clinical Study of Acupoint Catgut Embedding on Protracted Withdrawal Symptoms of Heroin Addicts
Objective:To observe the clinical effect of acupoint catgut embedding on protracted withdrawal symptoms of heroin addicts.Methods:A total of 30 patients with heroin addicts in a compulsory isolation drug rehabilitation center in Ningxia Hui Autonomous Region were randomly divided into the control group and the study group,with 15 cases in each group.The control group was interfered by the daily basic discipline project of the compulsory isolation drug rehabilitation center;on which basis,the study group was also treated with acupoint catgut embedding,once every 2 weeks.High-throughput 16SrDNA sequencing technology was used to detect the difference in intestinal microbial community structure between the two groups.The changes of physical symptoms,emotional symptoms,craving symptoms and sleep disorders were evaluated by heroin protracted withdrawal symptom rating scale before and after the intervention in the two groups.Results:After 2 months of treatment,the scores of heroin protracted withdrawal symptoms were lower in the study group than those in the control group(P＜0.01).Compared with those before the treatment,the chao and sobs indexes were decreased after the treatment in the two groups(P＜0.05).The OTU number and simpson index were higher after the treatment than those before the treatment in the study group,which were also higher than those after the treatment in the control group.Compared with those in the control group,the relative abundance of Actinobacteriota and Proteobacteria were increased in the study group after the treatment(P＜0.05,P＜0.01).The relative abundance of Ruminococcus was mainly increased after the treatment compared with that before the treatment in the study group(P＜0.05).The relative abundance of Bifidobacterium was increased in the study group than that in the control group after the treatment.LEfSe analysis showed that Bacilli,Lactobacilaceae and Lactobacillus were relatively abundant in the study group after the treatment.Conclusion:Acupoint catgut embedding therapy,which is based on nourishing Heart and calming Shen,regulating Qi and blood,tonifying Kidney-Yang,and strengthening Spleen and Stomach,increases beneficial bacteria through acupoint stimulation,improves intestinal function,alleviates symptoms of abnormal nervous system,and finally alleviates symptoms of heroin withdrawal.
万方数据
维普
