Effects of Du Meridian Moxibustion Combined with Wenshen Jianpi Jieyu Formula on Fatigue State,Oxidative Stress and Immune Function in Patients with Chronic Fatigue Syndrome
Objective:To investigate the effects of Du meridian moxibustion combined with Wenshen Jianpi Jieyu Formula on fatigue state,oxidative stress and immune function in patients with chronic fatigue syndrome(CFS).Methods:100 patients with CFS were randomly divided into the control group and the study group,with 50 cases in each group.The control group was treated with conventional Western medication;on which basis,the study group was also treated with Du meridian moxibustion combined with Wenshen Jianpi Jieyu Formula.Both groups were treated for 8 weeks.The scores of fatigue scale(FS-14),Qi deficiency syndrome,self-rating depression scale(SDS),Pittsburgh sleep quality index(PSQI),health survey summary(SF-36)were evaluated,the serum levels of oxidative stress indexes,including superoxide dismutase(SOD)and lipid peroxide(LPO),as well as the serum levels of CD4+and CD8+were detected before and after the treatment in the two groups.Results:The total effective rate of the study group 94.00％(47/50),which was significantly higher than 74.00％(37/50)in the control group(P＜0.05).After the treatment,the scores of FS-14 and Qi deficiency syndrome were significantly decreased in the study group compared with those in the control group(P＜0.05).The scores of SDS and PSQI were lower in the study group than those in the control group(P＜0.05),whereas the score of SF-36 was higher in the study group than that in the control group(P＜0.05).The level of SOD was higher and the level of LPO was lower in the study group than those in the control group(P＜0.05).The levels of CD4+and CD4+/CD8+were higher in the study group than those in the control group(P＜0.05).Conclusion:Du meridian moxibustion combined with Wenshen Jianpi Jieyu Formula can improve therapeutic effect and clinical symptoms in treatment of CFS.The mechanism may be related to the regulation of oxidative stress and immune function.
Chronic fatigue syndromeDu meridian moxibustionWenshen Jianpi Jieyu FormulaOxidative stressImmune function
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维普
