Influence of Needle-Warming Moxibustion on Periumbilical Four Sided Acupoints to Sleep Structure of Chronic Insomnia due to Deficiency of Heart and Spleen
Objective:To observe the influence of needle-warming moxibustion on periumbilical four sided acupoints to sleep structure of the patients with chronic insomnia disorder(CID)due to deficiency of Heart and Spleen.Methods:121 patients with CID due to deficiency of Heart and Spleen were randomly divided into the control group(n=61)and the study group(n=60).Both groups were treated with Jiawei Guipi Decoction;on which basis,the control group was also treated with needling Baihui(DU20),Shenmen(HT7),Anmian(HN-54),Neiguan(PC6)and Sanyinjiao(SP6),whereas the study group was also treated with needling DU20,HT7 and HN-54,as well as needling-warming moxibustion on periumbilical four sided acupoints.The treatment was performed 3 times a week for 4 weeks.The scores of PSQI and ISI,as well as the values of TST,SOL,SE,WASO,N1,N2,N3 and REM were compared between before and after the treatment in the two groups.The serum levels of 5-HT,DA and MT were detected by ELISA before and after the treatment in the two groups.Results:The scores of PSQI and ISI were decreased after the treatment in both groups(P＜0.05),and the decreases were more significant in the study group than those in the control group(P＜0.05).The values of TST,SE,N3％and REM％were significantly increased,whereas the values of SOL,WASO,N1％and N2％were significantly decreased in both groups after the treatment(P＜0.05).All the sleep structure parameters were better in the study group than those in the control group(P＜0.05).The serum levels of 5-HT and MT were increased(P＜0.05),and the serum level of DA was decreased after the treatment in the two groups(P＜0.05),and the improvements were more significant in the study group than those in the control group(P＜0.05).Conclusion:Needle-warming moxibustion on periumbilical four sided acupoints has a significant effect on chronic insomnia due to deficiency of Heart and Spleen,which can effectively improve the sleep structure and sleep quality,and regulate the serum levels of 5-HT,DA and MT.
Needle-warming moxibustionPeriumbilical four sided acupointsChronic insomnia disorderSleep structureDeficiency of Heart and Spleen syndrome
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