Effect of Fang's Scalp Acupuncture Combined with Nazi Method of Midnight-Noon Ebb-Flow on Serum GABA and Glu and Sleep Quality in Patients with Insomnia
Effect of Fang's Scalp Acupuncture Combined with Nazi Method of Midnight-Noon Ebb-Flow on Serum GABA and Glu and Sleep Quality in Patients with Insomnia
Objective:To explore the therapeutic efficacy of Fang's scalp acupuncture combined with Nazi method of midnight-noon ebb-flow in treatment of insomnia,and to explore its possible mechanisms.Methods:60 patients with insomnia were randomly divided into the observation group(n=30)and the control group(n=30,one case dropping out).The control group was treated with conventional acupuncture,whereas the observation group was treated with Fang's scalp acupuncture combined with Nazi method of midnight-noon ebb-flow.Both groups were needled once a day,5 times a week for 2 weeks.The score of Pittsburgh Sleep Quality Index(PSQI),and the serum levels of γ-aminobutyric acid(GABA)and glutamate(Glu)were assessed before and after the treatment in the two groups.Results:After 2 weeks of treatment,the score of PSQI was significantly decreased in both groups compared to that before the treatment in the two groups;the serum level of GABA was increased and the serum level of Glu was decreased compared to that before the treatment in the two groups.There was a statistical difference in the serum level of GABA between the two groups after the treatment(P＜0.05).Conclusion:Fang's scalp acupuncture combined with Nazi method of midnight-noon ebb-flow is indeed efficacious in treatment of insomnia,it can significantly improve the clinical symptoms,and its mechanism may be related to the regulation of serum levels of GABA and Glu.
关键词
失眠/方氏头针/子午流注纳子法/γ-氨基丁酸/谷氨酸/随机对照试验
Key words
Insomnia/Fang's scalp acupuncture/Nazi method of midnight-noon ebb-flow/GABA/Glu/Randomized controlled trial
维普
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