摘要
卵巢储备功能减退(DOR)是导致不孕的重要原因.目前,现代医学对DOR的治疗缺少共识性方法.针灸治疗DOR极具潜力.本研究总结近5年针灸治疗DOR的国内外临床及实验研究近况,包括针灸治疗DOR的取穴规律、刺灸法应用特点以及针刺对DOR患者生殖内分泌、卵巢组织形态、免疫系统、颗粒细胞凋亡、相关信号通路以及DOR患者妊娠及活产的影响,以期促进针灸在卵巢储备功能减退疾病的拓展应用.
Abstract
Diminished ovarian reserve(DOR)is a significant cause of infertility.Currently,there is a lack of consensus in modern medicine regarding the treatment of DOR.Acupuncture therapy shows great potential in treating DOR.This study summarized the recent clinical and experimental research on acupuncture treatment of DOR from domestic and international perspectives over the past five years.It includes the acupuncture point selection principle,characteristics of moxibustion application,and the effects of acupuncture on reproductive endocrine function,ovarian morphology,immune system,granulosa cell apoptosis,related signaling pathways,as well as the impact on pregnancy and live birth rates in patients with DOR.The aim is to promote the expanded application of acupuncture and moxibustion in treatment of DOR.
基金项目
国家自然科学基金青年项目(82004484)
中国中医科学院科技创新工程重大攻关项目(C12021A03502)
维普
万方数据