Research Progress on Clinical Efficacy and Mechanism of Acupuncture and Moxibustion in Treatment of PCOS
The relevant literature on the treatment of PCOS with TCM external therapies were retrieved from both domestic and foreign databases.After summarizing,the clinical observation indicators for TCM external therapies of PCOS include improvements in menstrual status,reduction in androgen levels,improvements of symptoms related to high androgen,improvement of endometrial receptivity,increase in ovulation rate,change of pregnancy outcome,reduction in body weight and improvement in insulin sensitivity.The TCM external therapies include acupuncture and moxibustion,acupoint catgut embedding,auricular needling.The potential effects of TCM external therapies mainly involve regulating hypothalamic-pituitary-ovarian axis,improving chronic inflammation,regulating PI3K/Akt/mTOR pathway,and improving intestinal flora.TCM external therapies may improve the clinical symptoms of PCOS by regulating endocrine,relieving inflammation and improving insulin sensitivity.
Polycystic ovary syndromeAcupuncture and moxibustionClinical efficacyMechanism