摘要
目的:利用CiteSpace软件对近30年关于电针治疗脑缺血再灌注损伤的相关文献进行分析,以揭示该领域的研究热点和发展趋势.方法:检索时间跨度为1994年1月1日-2023年10月18日的CNKI和WOS相关文献.运用CiteSpace和Excel软件从文献发表量、期刊、国家、机构、作者、引文和关键词等方面进行文献计量学分析.结果:共纳入725篇中文文献和328篇英文文献,平均年发文量整体呈上升趋势,中英文发文最多的期刊分别是《针刺研究》和Neural Regeneration Research;发文最多的国家是中国;中英文发文最多的机构分别为湖北中医药大学和福建中医药大学;发文最多的团队是陈立典-陶静团队.关键词共现分析显示,电针治疗脑缺血再灌注研究以动物实验为主,包括分子机制和细胞死亡机制.其中,细胞凋亡、炎症反应、自噬和氧化应激是重点领域.关键词突现分析显示,近年的研究热点以联合疗法和细胞焦亡为主.结论:目前缺乏大规模、多中心研究网络以及标准化的治疗方案和操作准则;侧重于基础研究.因此,未来的研究需要加强国内外合作,完善治疗方案和操作标准,拓宽研究领域,推动临床转化应用.
Abstract
Objective:To analyze the literature about electro-acupuncture(EA)in treatment of cerebral ischemia-reperfusion injury(CIRI)in the past 30 years by using CiteSpace software,thus to identify the research hotspots and trends in this field.Methods:Relevant literature were retrieved from CNKI and WOS,spanning from January 1,1994 to October 18,2023.The bibliometric analysis was performed in terms of publication volume,journals,countries,institutions,authors,citations and keywords by using the CiteSpace and Excel software.Results:A total of 725 Chinese literature and 328 English literature were included in the analysis,with an overall increasing trend in average annual publication.The journals with the highest number of publications in Chinese and English were Acupuncture Research and Neural Regeneration Research,respectively.China was the country with the highest number of publications,and Hubei University of Chinese Medicine and Fujian University of Traditional Chinese Medicine were the institutions with the highest number of publications in both languages.The team with the highest number of publications was led by CHEN Lidian and TAO Jing.Co-occurrence analysis of keywords indicated that the researches of EA treatment for CIRI primarily focused on animal experiments,including molecular mechanisms and cell death mechanisms researches,with apoptosis,inflammatory response,autophagy and oxidative stress being key areas.Keyword highlighted analysis showed that in recent years,the research hotspot has shifted to combination therapy and pyroptosis.Conclusion:Currently,there is a lack of large-scale,multi-center research networks as well as standardized treatment protocols and operational guidelines,but focus on basic research.Therefore,future search needs to enhance domestic and international collaboration,improve treatment protocols and operating standards,expand research areas,and promote clinical translational applications.
基金项目
国家自然科学基金(81973933)
安徽省第十三批115产业创新团队项目(皖人才办20204号)
安徽省高等学校科学研究项目(自然科学类)(2023AH040111)
安徽省名中医王颖工作室建设项目(中发展20225号)
国家科技期刊平台
NSTL
万方数据