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针刺治疗功能性消化不良的优化方案循证研究

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目的:对近20年来有关针刺治疗功能性消化不良的临床文献的相关要素进行了统计分析,以期为临床实践提供更高质量的参考依据.方法:通过文献计量学对影响针刺治疗功能性消化不良疗效的相关因素进行分析,这些关键因素包括取穴组方、针刺手法、行针时间、留针时间、针刺频次及疗程等.结果:针刺治疗FD使用频次排在前5位的腧穴由高到低依次为足三里、中脘、内关、天枢与太冲,其中又以足三里、中脘与内关3个穴位的使用频次较高.在最常用的8个穴位中,以胃经、膀胱经与任脉的穴位占比最高.关于穴位配伍,在针刺治疗FD的组方中,以足三里为主同时配伍中脘的组方最为常用,这种配伍概率高达83.70%.当以内关、足三里为主,同时取用中脘的概率也较高(84.62%).关于提插频率,只有少数文献(14.05%)有描述,其中多数(82.35%)选用的提插频率为60~90次/min.关于捻转频率,只有少数文献(29.75%)进行了描述,其中多数(66.67%)采用60~90 r/min.关于捻转幅度,只有少部分文献(29.75%)描述了捻转幅度,其中多数文献(61.11%)的捻转幅度为90°~180°.行针时间方面,只有少数文献(13.22%)有具体描述,其中多数(50.00%)选用的持续时间为10~30 s.关于行针的时间间隔,也只有少部分文献(32.23%)关注了这个问题,其中多数文献(92.31%)选用的时间间隔为5~10 min.留针时间方面,多数(81.82%)有具体描述,其中20~30 min为最常用的留针时间(80.81%).治疗频次方面,多数文献(90.91%)有具体描述,其中1次/d为最常选用的治疗频次(80.17%).疗程方面,多数文献(90.91%)有具体描述,其中80.17%的研究选用的疗程为3~4周.结论:针刺治疗功能性消化不良使用频次排在前5位的腧穴由高到低依次为足三里、中脘、内关、天枢与太冲,取用腧穴则以胃经、膀胱经的占比最高;足三里、中脘配伍,或足三里、中脘和内关配伍在各种针刺处方中最为常用;留针期间针刺的行针时长每次多为20 s左右,行针的时间间隔一般为5~10 min行针1次;留针时间多为20~30 min;治疗频次多为1次/d,疗程一般为3~4周.本研究根据大量临床实践经验循证所得,然而影响疗效的这些关键因素与疗效之间的确切关系尚需进行深入研究,因此针刺治疗功能性消化不良的方案具有较大的优化空间.
Evidence-Based Study on Optimization of Acupuncture Treatment Protocols for Functional Dyspepsia
Objective:A statistical analysis of relevant factors in clinical literature on acupuncture treatment for functional dyspepsia(FD)over the past 20 years was conducted to provide higher-quality references and guidelines for clinical practice.Methods:A bibliometric analysis was conducted to examine the factors influencing acupuncture treatment for functional dyspepsia.These key factors include acupoint selection and combinations,needling techniques,duration of needling,needling retention time,frequency of acupuncture sessions,and related outcomes.Results:The top five acupoints with the highest frequency of acupuncture treatment for FD were Zusanli(ST36),Zhongwan(RN12),Neiguan(PC6),Tianshu(ST25)and Taichong(LR3),among which ST36,RN12 and PC6 were the most frequently used acupoints.Among the most commonly used eight acupoints,those from the Stomach Meridian,Bladder Meridian and Ren Channel had the highest proportions.Regarding acupoint compatibility,in the acupuncture prescriptions for treating FD,the combination of ST36 and RN12 was the most commonly used,with a high compatibility rate of 83.70%.When PC6 and ST36 were the primary points,the probability of also using RN12 was relatively high(84.62%).As for the lifting and thrusting frequency,only a few studies(14.05%)provided prescriptions,with the majority(82.35%)using a frequency of 60-90 times min.Regarding the twirling frequency,only a few studies(29.75%)provided descriptions,with the majority(66.67%)using a frequency of 60-90 times/min.Regarding the twirling amplitude,only a few studies(29.75%)described it,with most(61.11%)reporting an amplitude of 90-180°.For the duration of needling,only a few studies(13.22%)provided specific descriptions,with most(50.00%)selecting a duration of 10-30 seconds.Concerning the intervals between needling,only a few studies(32.23%)addressed this issue,with most(92.31%)reporting an interval of 5-10 minutes.In terms of needle retention time,most studies(81.82%)provided specific descriptions,with 20-30 minutes being the most commonly used duration(80.81%).In terms of treatment frequency,most studies(90.91%)described it specifically,with once per day being the most common frequency(80.17%).Considering treatment course,most studies(90.91%)had specific descriptions,with 80.17%of the studies selecting a course duration of 3-4 weeks.Conclusion:The top five acupoints used for acupuncture treatment of FD,in order of frequency,are ST36,RN12,PC6,ST25 and LR3.The most commonly selected meridians are the Stomach Meridian and Bladder Meridian.The combination of ST36 and RN12,or ST36,RN12 and PC6 is most frequently used in various acupuncture prescriptions.During needle retention,the duration of needling each time is usually about 20 seconds,with intervals of 5-10 minutes between needling sessions.The needle retention time is mostly 20-30 minutes,with a treatment frequency of once per day and a treatment course of 3-4 weeks.This recommended protocol is derived from extensive clinical practice and evidence-based research.However,the exact relationship between these key factors and treatment efficacy requires further investigation.Therefore,there is significant space for optimization in the acupuncture treatment protocol for FD.

Functional dyspepsiaAcupunctureBibliometricsOptimized planEvidence-based study

陈碧玮、张丽丽、陈少宗

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山东中医药大学针灸推拿学院,山东济南 250355

山东中医药大学针灸研究院,山东济南 250355

功能性消化不良 针刺 文献计量学 优化方案 循证研究

国家重点研发计划

2022YFC3500602

2024

针灸临床杂志
中华中医药学会 黑龙江中医药大学 中国针灸学会临床分会

针灸临床杂志

CSTPCD
影响因子:1.242
ISSN:1005-0779
年,卷(期):2024.40(10)