首页|脑神经环路常用技术及其在针灸领域应用研究

脑神经环路常用技术及其在针灸领域应用研究

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神经环路对大脑的信息传递与处理有着至关重要的作用.脑内神经环路异常是很多脑疾病临床表型的核心基础,探索神经环路对于预防与治愈脑疾病意义重大.如何能高效观测(即具有高时间、空间和细胞类型分辨率)神经环路是神经科学研究中一直探寻的方向.本研究就现阶段广泛应用的神经示踪技术、光遗传学、化学遗传学、钙成像-光纤记录及电生理技术等的应用研究进行探讨,对以上技术在针灸领域(吞咽障碍、消化和疼痛等)的应用进行述评,以期为神经环路相关研究提供新思路.
Common Techniques for Studying Neural Circuits and Their Application in Acupuncture Research
Neural circuits play a crucial role in the transmission and processing of information in the brain.Abnormalities in the brain neural circuit are the core basis of the clinical phenotypes of neurological diseases,making the exploration of neural circuit significant for the prevention and treatment of these conditions.Achieving efficient observation of neural circuits,with high temporal,spatial and cell type resolution,has been a key objective in neuroscience research.This study aims to explore the current applications of widely used techniques such as neural tracing,optogenetics,chemogenetics,calcium imaging-fiber photometry and electrophysiology.Additional,it reviews the application progress of these technologies in the field of acupuncture,particularly in the treatment of conditions like dysphagia,digestion and pain.The goal is to provide new insights and references for neural circuit-related research.

Neural circuitOptogeneticsChemogeneticsCalcium imaging-fiber recording technique

梁越、张宁、赵耀、吕沛然、谢璐霜、刘奇、乔海法、余曙光、赵娴

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陕西中医药大学,陕西咸阳 712046

成都中医药大学,四川成都 610075

神经环路 光遗传学 化学遗传学 钙成像-光纤记录技术

2024

针灸临床杂志
中华中医药学会 黑龙江中医药大学 中国针灸学会临床分会

针灸临床杂志

CSTPCD
影响因子:1.242
ISSN:1005-0779
年,卷(期):2024.40(11)