Research Progress on Involvement of Prefrontal Cortex and Hippocamus in Mechanisms of Acupuncture Intervention for Depression
Depression is a common mental disorder that garners attention due to its high suicide rate and high disability rate.Although its underlying pathological mechanisms remain unclear,known neural damage primarily occurs in the prefrontal cortex and hippocampus,both of which are closely related to the pathological mechanism of depression.While Western medicine shows significant effects in treating depression,it is often accompanied by side effects,poor compliance and potential drug resistance.In contrast,increasing clinical research indicates that acupuncture therapy has notable efficacy with fewer side effects.In order to further investigate the pathological mechanism of depression and achieve better treatment outcomes,this study conducts a comprehensive analysis of literature from the past five years.It focuses on elucidating the crucial roles of the prefrontal cortex and hippocampus in the pathological mechanism of depression and explores the mechanisms of acupuncture intervention related to these regions.This review aims to support the advancement of acupuncture therapy and the generation of new therapeutic approaches,thereby enhancing its credibility.
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