首页|基于脑肠轴理论探讨针灸治疗帕金森病的效应机制

基于脑肠轴理论探讨针灸治疗帕金森病的效应机制

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帕金森病(PD)作为一种常见的神经退行性病变,其诊断和治疗一直是学术界研究的热点.近年来脑肠轴已被证明与PD的发生发展相关.针灸作为一种非药物治疗手段,一定程度上能改善PD患者的运动障碍及非运动症状.本研究通过探讨近年来有关脑肠轴对PD的影响以及针灸治疗PD作用机制,发现针灸可通过调节肠道菌群、迷走神经、神经-内分泌系统及神经-免疫系统影响脑肠轴,进而起到缓解PD病情、延缓PD病程的效果.因此,针灸通过调节脑肠轴影响PD或许能够开拓防治PD的新视野.
Exploring Mechanism of Acupuncture and Moxibustion in Treatment of PD Based on Brain-Gut Axis Theory
Parkinson's disease(PD)is a common neurodegenerative disorder,and its diagnosis and treatment have been key research topics in the academic community.In recent years,the brain-gut axis has been proven to be closely related to the onset and progression of PD.Acupuncture and moxibustion,as non-pharmacological treatments,has been shown to improve both motor and non-motor symptoms in PD patients to some extent.This study,through exploring the effects of the brain-gut axis on PD and the mechanisms of acupuncture and moxibustion in PD treatment,reveals that acupuncture and moxibustion can influence the brain-gut axis by regulating gut mocrobiota,the vagus nerve,the neuro-endocrine system,and the neuro-immune system,which in turn helps alleviate PD symptoms and slow the progression of the disease.Therefore,acupuncture and moxibustion's modulation of the brain-gut axis may offer new insights into the prevention and treatment of PD.

Parkinson's diseaseAcupuncture and moxibustionBrain-gut axisAction mechanism

范诗宇、孙雨佳、闫隆、钱玉林、于涛

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天津中医药大学第一附属医院国家中医针灸临床医学研究中心,天津 300380

天津中医药大学,天津 301617

帕金森病 针灸 脑肠轴 作用机制

2024

针灸临床杂志
中华中医药学会 黑龙江中医药大学 中国针灸学会临床分会

针灸临床杂志

CSTPCD
影响因子:1.242
ISSN:1005-0779
年,卷(期):2024.40(12)