Research Progress on EA Regulating Programmed Cell Death in Treatment of CIRI
Cerebral ischemia-reperfusion injury(CIRI)is a secondary injury that occurs during the restoration of blood supply following ischemic stroke.This process involves multiple mechanisms of programmed cell death,including autophagy,apoptosis,pyroptosis,necroptosis,ferroptosis and cuprotosis.Increasing evidence suggests that electro-acupuncture(EA)can regulate these forms of cell death to alleviate brain tissue damage.This review made an exploration the regulation of programmed cell death by EA in treatment of CIRI.