首页|植物生长素原初响应基因Aux/IAA研究进展

植物生长素原初响应基因Aux/IAA研究进展

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  • 国家科技期刊平台
  • NETL
  • NSTL
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  • 维普
Aux/IAA基因家族能够在生长素诱导的早期做出响应,是生长素早期应答的3类基因家族之一.ARF则是一类调控生长素响应基因表达的转录因子,Aux/IAA就是通过其响应元件与ARF特异性结合,从而调节生长素早期应答基因的转录功能.介绍了Aux/IAA的结构特征、调控机制以及生物学功能.植物Aux/IAA基因是由4个保守结构域组成的:结构域Ⅰ,Ⅱ,Ⅲ和Ⅳ.结构域Ⅰ主要负责Aux/IAA蛋白的阻遏作用,结构域Ⅱ因为含有一段亮氨酸基序,负责Aux/IAA蛋白的快速降解,而结构域Ⅲ和Ⅳ则介导Aux/IAA蛋白与ARF蛋白形成同源或异源二聚体.在生长素信号转导过程中,Aux/IAA主要通过与生长素响应因子ARF结合,促进早期基因转录,从而调节下游基因的表达.Aux/IAA基因因其种类不同在不同的组织和器官中的表达是有特异性的,同时通过Aux/IAA突变体的研究表明:不同的Aux/IAA还具有各自独特的功能.不论是由于时间和空间表达上的不同,还是由于其基因的启动子对生长素响应因子的亲合性差异都能产生这些功能特异性.而植物激素和外界环境因子对发挥Aux/IAA功能也具有重要的调控作用.
Advances in primary auxin-responsive Aux/IAA gene family: a review
Members of Aux/IAA gene family are responsive to primary auxin induction.ARF is a kind of regulating auxin response gene expression to regulate auxin primary function of gene transcription.By combining its response elements with the specificity of ARF,Aux/IAA is a transcription function to regulate primary auxinresponsive gene.This paper reviewed the recent advances in the structural characteristics,regulation mechanism and biological functions of Aux/IAAs.Aux/IAAs consisted of four conserved domains:Domains Ⅰ,Ⅱ,Ⅲ and Ⅳ.Domain Ⅰ was responsible for the protein inhibition of Aux/IAAs.With a leucine motif,Domain Ⅱ was capable of rapid protein stability.Domains Ⅲ and Ⅳ were responsible for protein dimerization (homo-and hetero-dimerization).Aux/IAAs promoted the transcription of early genes by combining auxin response factors,and they regulated the expression of downstream genes in the process of auxin signal transduction.Different Aux/IAAs were expressed in different tissues and organisms.Also,the study of Aux/IAA mutants indicated that different Aux/IAAs had different functions due to differences in temporal and spatial expression and affinities with promoters of Aux/IAA genes to the ARF gene.Plant hormones and environmental factors also had important roles in regulating Aux/IAAs.

biochemistry molecular biologyprimary auxin-responsive gene (Aux/IAA)gene functionregulation mechanismreview

司马晓娇、郑炳松

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浙江农林大学亚热带森林培育省部共建国家重点实验室培育基地,浙江临安311300

生物化学与分子生物学 生长素原初响应基因Aux/IAA 基因功能 调控机制 综述

国家自然科学基金资助项目国家自然科学基金资助项目国家自然科学基金资助项目浙江省自然科学基金资助项目

314706833127071631070604LR13C160001

2015

10.11833/j.issn.2095-0756.2015.02.021

浙江农林大学学报
浙江农林大学

浙江农林大学学报

CSTPCDCSCD北大核心
影响因子：0.929
ISSN：2095-0756
年,卷(期)：2015.32(2)
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